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levitra vente This result demonstrated that the nanoparticle can provide several advantages for multidrug co delivery compared with combinations of free drugs solution form such as 1 nanoparticles can deliver hydrophobic and hydrophilic drugs at the same time and maintain the optimized synergistic drug ratio in a single nanoparticle, 2 nanoparticles can elongate circulation time and enhance tumor targeting ability of drugs, and 3 drug encapsulated nanoparticles can deliver multidrugs into a target cell simultaneously that will normalize the pharmacokinetic difference between drugs